The mission of Jackson Memorial Foundation is to conduct traditional philanthropic activities and to independently create and implement other strategic entrepreneurial initiatives that financially assist Jackson Memorial Hospital in advancing its status as a world-class medical center.

The Foundation has additional support groups, including the Golden Angel Society, Guardian Angels, and International Kids Fund Wonderfund™. The Golden Angel Society is Jackson Memorial Foundation's prestigious donor recognition club. Guardian Angels are dedicated to providing the very best medical care possible for children being cared for at Holtz Children's Hospital. International kids Fun Wonderfund™ is a global outreach program seeking to provide medical care to children from around the world, who cannot be treated in their home countries.

In addition, Foundation Health Services, Inc., is a wholly-owned and operated, nonprofit subsidiary of Jackson Memorial Foundation. Since its creation in 2006, Foundation Health Services has become one of the most rapidly growing revenue producers for the Jackson Memorial Hospital. Additionally, Foundation Health Services operates Foundation Health Services Hospitality and Concierge Service, a customer-service-focused program for inpatient customer service and premium-pay amenities.